Sepsis and Inflammatory Disorders - A New Diagnostic Opportunity

Front view of the imiwn sTLR2 box, magenta in colour on a white background reflecting the bottom of the box.

Sepsis and inflammatory disorders - a new diagnostic opportunity

The imiwn sTLR2 RAPID test is a UKCA certified in vitro diagnostic immunochromatographic assay for the semi-quantitative measurement of human soluble Toll-like receptor 2 (sTLR2) in serum - a biomarker of inflammation and sepsis. The level of sTLR2 in serum has the potential to provide additional information to that of traditional biomarkers such as C-reactive protein (CRP).

The sTLR2 rapid test addresses a significant gap in the sepsis diagnostic market, providing scientists and clinicians with a new, potentially transformative tool, and additional opportunities for decision making and health outcomes.

Developed by a UK based innovative biotech company, with proven technology and a defined roadmap for scalability, the company is positioned for rapid growth through strategic partnerships to reach a broad market, whilst supporting research into additional diagnostic applications and platforms.

UK Patent Application GB2502531.3.

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Soluble Toll-like receptor 2

A soluble form of Toll-like receptor 2 (sTLR2) is present in human plasma and amniotic fluid, and shows anti-inflammatory potential. It is released early upon infection/cell activation and acts as a decoy receptor to limit inflammation. Elevated levels of sTLR2 may be present early on in patients with sepsis, and other infective and inflammatory conditions.

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imiwn sTLR2 lateral flow test cassette showing two magenta coloured lines for test and control respectively.

Results in 10 minutes

Semi-quantitative results from a 20µL serum sample in 10 minutes. The human sTLR2 rapid test kit uses proprietary sTLR2 monoclonal antibodies in a simple, convenient lateral flow format. Each kit contains 10 test devices.

Download sTLR2 Rapid Instructions for Use

Lateral flow assay development showing a close up of a dispensor for positive and negative controls.

Quality assured

Developed and manufactured in the UK according to a fully certified medical device quality assurance system (ISO13485).

UKCA Certified.

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